Alzheimer s Prevention Initiative: a proposal to evaluate presymptomatic treatments as quickly as possible

• Published in: Biomarkers in medicine Vol. 4; no. 1; pp. 3 - 14
• Main Authors: Reiman, Eric M, Langbaum, Jessica BS, Tariot, Pierre N
• Format: Journal Article
• Language: English
• Published: Future Medicine Ltd 01.02.2010
• Subjects: amyloid; apolipoprotein; biomarker; clinical trial; genetics; MRI; PET; presenilin; public policy; surrogate marker

Now is the time to launch the era of Alzheimer s disease (AD) prevention research, establish the methods and infrastructure to rapidly evaluate presymptomatic AD treatments and evaluate them rigorously and rapidly in randomized clinical trials. This article is a call to arms. It contends that the ev...