Unigenic evolution: a novel genetic model localizes a putative leucine zipper that mediates dimerization of the Saccharomyces cerevisiae regulator Gcr1p

• Published in: Genetics (Austin) Vol. 141; no. 4
• Main Authors: Deminoff, S.J. (University of Southern Mississippi, Hattiesburg, MS.), Tornow, J, Santangelo, G.M
• Format: Journal Article
• Language: English
• Published: 01.12.1995
• Subjects: ADN; MUTACION; MUTACION INDUCIDA; MUTANT; MUTANTES; MUTATION; MUTATION PROVOQUEE; PROTEINAS AGLUTINANTES; PROTEINE DE LIAISON; SACCHAROMYCES CEREVISIAE

The GCR1 gene of Saccharomyces cerevisiae encodes a transcriptional activator that complexes with Rap1p and, through UAS(RPG) elements (Rap1p DNA binding sites), stimulates efficient expression of glycolytic and translational component genes. To map the functionally important domains in Gcr1p, we co...