Concentrations of adipsin in blood and rates of adipsin secretion by adipose tissue in humans with normal, elevated and diminished adipose tissue mass

• Published in: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity Vol. 18; no. 4; pp. 213 - 218
• Main Authors: Napolitano, A, Lowell, B.B, Damm, D, Leibel, R.L, Ravussin, E, Jimerson, D.C, Lesem, M.D, Van Dyke, D.C, Daly, P.A, Chatis, P
• Format: Publication
• Language: English
• Published: 1994
• Subjects: adipose tissue; anorexia nervosa; body weight; complement; men; obesity; women

Adipsin, which is identical to complement factor D, is synthesized by fat cells, circulates in the bloodstream and is profoundly deficient in mice with genetic and hypothalamic obesity. With the recent cloning of human adipsin, a quantitative human immunoassay has been developed. In the present stud...