Immunohistochemical localization of CYP1A, vitellogenin and Zona radiata proteins in the liver of swordfish (Xiphias gladius L.) taken from the Mediterranean Sea, South Atlantic, South Western Indian and Central North Pacific Oceans

• Published in: Aquatic toxicology Vol. 71; no. 18; pp. 1 - 12
• Main Authors: Desantis, S, Corriero, A, Cirillo, F, Deflorio, M, Brill, R, Griffiths, M, Lopata, A.L, Serna, J.M. de la, Bridges, C.R, Kime, D.E
• Format: Journal Article
• Language: English
• Published: 2005
• Subjects: biliary tract; biomarkers; blood vessels; cytochrome P-450; egg proteins; endocrine-disrupting chemicals; endothelium; fish eggs; gene induction; hepatocytes; histology; immunohistochemistry; liver; marine fish; organic compounds; oxygenases; vitellogenin; water pollution; xenobiotics; Xiphias gladius; Indian Ocean; Atlantic Ocean; Pacific Ocean; Mediterranean Sea

Cytochrome P4501A (CYP1A) monoxygenase, vitellogenin (Vtg) and Zona radiata proteins (Zrp) are frequently used as biomarkers of fish exposure to organic contaminants. In this work, swordfish liver sections obtained from the Mediterranean Sea, the South African coasts (South Atlantic and South Wester...