Dissection of a circadian oscillation into descrete domains

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 94
• Main Authors: Merrow M.W, Garceau N.Y, Dunlap J.C
• Format: Journal Article
• Language: English
• Published: 1997
• Subjects: arn mensajero; arn messager; biological rhythms; expresion genica; expression des genes; gene expression; genetica; genetics; genetique; loci; locus; messenger rna; neurospora crassa; ritmos biologicos; rythme biologique; transcripcion; transcription

The circadian oscillator in Neurospora is a negative feedback loop involving as principal players the products of the frequency (frq) locus. frq encodes multiple forms of its protein product FRQ, which act to depress the amounts of frq transcript. In this scheme there are two discrete and separable...