PIPERAZINEDIONES HAVING A PSYCHOTROPIC ACTION

• Main Authors: ULRICH LERCH, GABRIELE WIEMER, RAINER HENNING, HANSJOERG URBACH, FRANZ HOCK, WOLFGANG RUEGER, WOLF-ULRICH NICKEL
• Format: Patent
• Language: English
• Published: 30.05.1990
• Edition: 5
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to compounds of the formula I (I) in which R1, R2 and R4 represent optionally substituted aliphatic, alicyclic, alicyclic-aliphatic, aromatic, araliphatic, heteroaromatic or heteroaromatic-aliphatic radicals, with R2, if not already covered by the above-mentioned definitions, denoting the side-chain, which is protected if necessary, of a naturally occurring alpha -amino acid, R4 can additionally represent R3 denotes an optionally substituted aliphatic, alicyclic, aromatic or araliphatic radical, or R3 and R4 form, together with the atoms carrying them, a mono-, bi- or tricyclic heterocyclic ring system, agents containing these, and the use thereof as pharmaceuticals having a psychotropic action for the prophylaxis of disorders of the central nervous system, especially having a nootropic action for the treatment of cognitive dysfunctions.