ANTI-IL-36 ANTIBODIES AND METHODS OF USE THEREOF

The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36α, IL-36β, and/or IL-36γ, and block the IL-36 stimulated signaling pathways. Compositions comprising such binding proteins and methods of making...

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Main Authors THAI, Tina, BHARILL, Shashank, FUH-KELLY, Germaine, PATEL, Ashka, KARRER, Erik, Edward, LEE, Chingwei, Vivian, SCHARF, Louise
Format Patent
LanguageEnglish
Published 26.10.2022
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Abstract The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36α, IL-36β, and/or IL-36γ, and block the IL-36 stimulated signaling pathways. Compositions comprising such binding proteins and methods of making and using such binding proteins are also provided.
AbstractList The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36α, IL-36β, and/or IL-36γ, and block the IL-36 stimulated signaling pathways. Compositions comprising such binding proteins and methods of making and using such binding proteins are also provided.
Author LEE, Chingwei, Vivian
BHARILL, Shashank
THAI, Tina
FUH-KELLY, Germaine
KARRER, Erik, Edward
PATEL, Ashka
SCHARF, Louise
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– fullname: LEE, Chingwei, Vivian
– fullname: SCHARF, Louise
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Snippet The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36α,...
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Title ANTI-IL-36 ANTIBODIES AND METHODS OF USE THEREOF
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