Novel gene disruptions, compositions and methods relating thereto

• Main Authors: IRVING, BRYAN, SPARKS, MARY JEAN, SEVAUX, TRACY ELLEN WILLIS, RANGEL, CAROLINA, FAN, LIANGFEN, MINZE, LAURIE JEANETTE, SHI, ZHENG-ZHENG, MCLAIN, DINA REBECCA, MONTGOMERY, CHARLES A, VOGEL, PETER, COMBS, KATHERIN E, TOWNSEND, TERESA GAIL, STALA, JOY ANNE, PHILLIPS, HEIDI, HORNER, ALLISON ANNE BYERS, PAYNE, BOBBY JOE, FILVAROFF, ELLEN, DESAUVAGE, FREDERIC, JUNUTULA, JAGATH REDDY, MASSEY, ERIN MARIE
• Format: Patent
• Language: English
• Published: 31.03.2010
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; NEW BREEDS OF ANIMALS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; TRAPPING

The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO218, PRO228, PRO271, PRO273, PRO295, PRO302, PRO305, PRO326, PRO386, P...