INSECT SIGNAL PEPTIDE MEDIATED SECRETION OF RECOMBINANT PROTEINS

• Main Authors: CLARK, ROBIN, PIATAK, MICHAEL, DEVLIN, PATRICIA E, O'ROURKE, EDWARD, C
• Format: Patent
• Language: English
• Published: 31.05.1990
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMES; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Novel DNA, plasmid and viral constructs are described for enhanced expression and secretion of proteins in various host cells, preferably insect cells, consisting of DNA sequences that encode insect cell signal peptide sequences associated with DNA sequences that encode heterologous proteins along w...