NOVEL MEGAKARYOCYTIC COLONY STIMULATING FACTOR AND PROCESS FOR ITS PREPARATION

• Main Authors: MATSUNAGA, KEITA, OGATA, KIYOYUKI, MAKABE, OSAMU, KURIYA, SHINICHIRO, HAMAGUCHI, HIROYUKI, NOJIRI, CHUHEI
• Format: Patent
• Language: English; Japanese
• Published: 05.04.1990
• Edition: 4
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

According to this invention, a novel megakaryocytic colony stimulating factor is obtained by culturing a cell strain of human pulmonary large cell cancer, for example, PC-13 cell strain or human lung cancer cell strain MC-1 separated as monoclonal cells from PC-13 cell strain, recovering a supernata...