HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
The present disclosure relates to compounds of Formula (I) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for modulating PARP1 activity and may be used in the treatmen...
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| Main Authors | , , |
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| Format | Patent |
| Language | English French |
| Published |
29.08.2024
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present disclosure relates to compounds of Formula (I) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for modulating PARP1 activity and may be used in the treatment of disorders in which PARP1 activity is implicated, such as cancer.
La présente invention concerne des composés de formule (I) et leurs promédicaments, des sels pharmaceutiquement acceptables, des compositions pharmaceutiques, des procédés d'utilisation et des procédés pour les préparer. Les composés de l'invention sont utiles pour moduler l'activité de PARP1 et peuvent être utilisés dans le traitement de troubles dans lesquels l'activité de PARP1 est impliquée, tels que le cancer. |
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| AbstractList | The present disclosure relates to compounds of Formula (I) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for modulating PARP1 activity and may be used in the treatment of disorders in which PARP1 activity is implicated, such as cancer.
La présente invention concerne des composés de formule (I) et leurs promédicaments, des sels pharmaceutiquement acceptables, des compositions pharmaceutiques, des procédés d'utilisation et des procédés pour les préparer. Les composés de l'invention sont utiles pour moduler l'activité de PARP1 et peuvent être utilisés dans le traitement de troubles dans lesquels l'activité de PARP1 est impliquée, tels que le cancer. |
| Author | PHAM, Son Minh PETTIGREW, Jeremy D KANKANALA, Jayakanth |
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| Discipline | Medicine Chemistry Sciences |
| DocumentTitleAlternate | COMPOSÉS HÉTÉROCYCLIQUES ET PROCÉDÉS POUR LES UTILISER |
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| Snippet | The present disclosure relates to compounds of Formula (I) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of... |
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| Title | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF |
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