STAPLED PEPTIDES AND METHODS THEREOF
Among other things, the present disclosure provides various useful agents. In some embodiments, provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides technologies for modulating beta-catenin functions. In some embodiments, the present disclosure provides tech...
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| Main Authors | , , , , , , , , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
20.06.2024
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Among other things, the present disclosure provides various useful agents. In some embodiments, provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides technologies for modulating beta-catenin functions. In some embodiments, the present disclosure provides technologies for preventing and/or treating conditions, disorders or diseases associated with beta-catenin. In some embodiments, the present disclosure provides designed amino acids and agents which can provide improved properties and/or activities.
Entre autres, la présente invention concerne divers agents utiles. Dans certains modes de réalisation, les agents de l'invention peuvent se lier à la bêta-caténine. Dans certains modes de réalisation, la présente invention concerne des technologies pour moduler des fonctions de bêta-caténine. Dans certains modes de réalisation, la présente invention concerne des technologies pour prévenir et/ou traiter des états, des troubles ou des maladies associés à la bêta-caténine. Dans certains modes de réalisation, la présente invention concerne des acides aminés et des agents conçus qui peuvent assurer des propriétés et/ou des activités améliorées. |
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| AbstractList | Among other things, the present disclosure provides various useful agents. In some embodiments, provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides technologies for modulating beta-catenin functions. In some embodiments, the present disclosure provides technologies for preventing and/or treating conditions, disorders or diseases associated with beta-catenin. In some embodiments, the present disclosure provides designed amino acids and agents which can provide improved properties and/or activities.
Entre autres, la présente invention concerne divers agents utiles. Dans certains modes de réalisation, les agents de l'invention peuvent se lier à la bêta-caténine. Dans certains modes de réalisation, la présente invention concerne des technologies pour moduler des fonctions de bêta-caténine. Dans certains modes de réalisation, la présente invention concerne des technologies pour prévenir et/ou traiter des états, des troubles ou des maladies associés à la bêta-caténine. Dans certains modes de réalisation, la présente invention concerne des acides aminés et des agents conçus qui peuvent assurer des propriétés et/ou des activités améliorées. |
| Author | VERDINE, Gregory L HUROV, Jonathan Barry SI, Yaguang LI, Zhi ORTET, Paula Cristina LING, Kevin DU, Peicheng WHITE, Brian Halbert TREMBLAY, Martin Robert CAPPUCCI, Sarah Isabelle MCGEE, John Hanney LA, Daniel Seungduk ALFARO-LOPEZ, Lorenzo Josue |
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| Snippet | Among other things, the present disclosure provides various useful agents. In some embodiments, provided agents can bind to beta-catenin. In some embodiments,... |
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| Title | STAPLED PEPTIDES AND METHODS THEREOF |
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