NOR1 LIGANDS AND METHODS OF THEIR USE

• Main Authors: YOON, Ho Sup, YOO, Jun Yeob
• Format: Patent
• Language: English; French
• Published: 23.05.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Various embodiments relate generally to ligands that bind to the neuron-derived orphan receptor-1 protein-ligand binding domain (Nor1-LBD) and modulate the activity of Nor1, and methods of using Nor1-modulating ligands. In particular, through structural characterisation of the ligand binding domain...