BROADLY NEUTRALIZING ANTIBODIES AGAINST INFLUENZA NEURAMINIDASE
The instant disclosure provides antibodies and antigen-binding fragments thereof that can bind to an influenza virus neuraminidase (NA) and can neutralize an influenza virus infection. Also provided are polynucleotides that encode an antibody, vectors that comprise such polynucleotides, host cells t...
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| Main Authors | , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
30.11.2023
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| Online Access | Get full text |
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| Abstract | The instant disclosure provides antibodies and antigen-binding fragments thereof that can bind to an influenza virus neuraminidase (NA) and can neutralize an influenza virus infection. Also provided are polynucleotides that encode an antibody, vectors that comprise such polynucleotides, host cells that can express the antibodies, related compositions, and methods of using the herein disclosed compositions to, for example, treat or prevent an influenza infection.
La présente invention concerne des anticorps et des fragments de liaison à l'antigène de ceux-ci qui peuvent se lier à une neuraminidase du virus de la grippe (NA) et peuvent neutraliser une infection par le virus de la grippe. L'invention concerne également des polynucléotides qui codent pour un anticorps, des vecteurs qui comprennent de tels polynucléotides, des cellules hôtes qui peuvent exprimer les anticorps, des compositions associées, et des procédés d'utilisation des compositions de l'invention pour, par exemple, traiter ou prévenir une infection par la grippe. |
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| AbstractList | The instant disclosure provides antibodies and antigen-binding fragments thereof that can bind to an influenza virus neuraminidase (NA) and can neutralize an influenza virus infection. Also provided are polynucleotides that encode an antibody, vectors that comprise such polynucleotides, host cells that can express the antibodies, related compositions, and methods of using the herein disclosed compositions to, for example, treat or prevent an influenza infection.
La présente invention concerne des anticorps et des fragments de liaison à l'antigène de ceux-ci qui peuvent se lier à une neuraminidase du virus de la grippe (NA) et peuvent neutraliser une infection par le virus de la grippe. L'invention concerne également des polynucléotides qui codent pour un anticorps, des vecteurs qui comprennent de tels polynucléotides, des cellules hôtes qui peuvent exprimer les anticorps, des compositions associées, et des procédés d'utilisation des compositions de l'invention pour, par exemple, traiter ou prévenir une infection par la grippe. |
| Author | MOMONT, Corey PIZZUTO, Matteo Samuele HAUSER, Kevin E CAMERONI, Elisabetta SNELL, Gyorgy CORTI, Davide |
| Author_xml | – fullname: CAMERONI, Elisabetta – fullname: PIZZUTO, Matteo Samuele – fullname: CORTI, Davide – fullname: HAUSER, Kevin E – fullname: SNELL, Gyorgy – fullname: MOMONT, Corey |
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| DocumentTitleAlternate | ANTICORPS LARGEMENT NEUTRALISANTS DIRIGÉS CONTRE LA NEURAMINIDASE DE LA GRIPPE |
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| RelatedCompanies | VIR BIOTECHNOLOGY, INC HUMABS BIOMED SA |
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| Snippet | The instant disclosure provides antibodies and antigen-binding fragments thereof that can bind to an influenza virus neuraminidase (NA) and can neutralize an... |
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| Title | BROADLY NEUTRALIZING ANTIBODIES AGAINST INFLUENZA NEURAMINIDASE |
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