COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E

• Main Authors: LOPEZ, Magdalena Preciado, REMARCIK, Clint, TAO, Jason, QUARTARARO, Anthony J, PENTELUTE, Bradley L, EATON, Dan, WONG, Jeffrey Ying-Kit, RÖSSLER, Simon L, BUCHWALD, Stephen L, LOAS, Andrei, WANG, John, GROB, Nathalie M
• Format: Patent
• Language: English; French
• Published: 11.07.2024
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

This disclosure relates to synthetic peptides, peptidomimetics, and complexes of synthetic peptides and peptidomimetics with HLA-E, methods of making such peptides, peptidomimetics, and complexes, and methods of using such peptides, peptidomimetics and complexes for blocking, inhibiting, or preventi...