COMPOSITIONS HAVING IMPROVED BIOAVAILABILITY OF THERAPEUTICS AND USES THEREOF
The present specification discloses pharmaceutical composition disclosed herein comprises one or more fibrates, one or more glycerolipids, and one or more digestion enhancers. The disclosed glycerolipids comprise one or more hard fats and one or more liquid fats. The disclosed digestion enhancers co...
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| Main Authors | , , |
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| Format | Patent |
| Language | English French |
| Published |
21.09.2023
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| Online Access | Get full text |
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| Abstract | The present specification discloses pharmaceutical composition disclosed herein comprises one or more fibrates, one or more glycerolipids, and one or more digestion enhancers. The disclosed glycerolipids comprise one or more hard fats and one or more liquid fats. The disclosed digestion enhancers comprise one or more bile acids, one or more phospholipids, one or more free C14-24 fatty acids, one or more free C14-24 fatty acid surfactants, or any combination thereof. The present specification also discloses methods and procedures to formulate the disclosed one or more fibrates into the disclosed pharmaceutical compositions. The present specification further discloses methods and uses of the disclosed pharmaceutical compositions in the treatment of an inflammation and/or neuroinflammation.
La présente invention divulgue une composition pharmaceutique comprenant un ou plusieurs fibrates, un ou plusieurs glycérolipides et un ou plusieurs activateurs de digestion. Les glycérolipides divulgués comprennent une ou plusieurs graisses solides et une ou plusieurs graisses liquides. Les amplificateurs de digestion divulgués comprennent un ou plusieurs acides biliaires, un ou plusieurs phospholipides, un ou plusieurs acides gras libres en C14-24, un ou plusieurs tensioactifs d'acides gras libres en C14-24 ou une combinaison quelconque associée. La présente invention divulgue également des méthodes et des procédures destinées à formuler lesdits un ou plusieurs fibrates divulgués dans les compositions pharmaceutiques divulguées. La présente invention divulgue en outre des méthodes et des utilisations des compositions pharmaceutiques divulguées dans le traitement d'une inflammation et/ou d'une neuro-inflammation. |
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| AbstractList | The present specification discloses pharmaceutical composition disclosed herein comprises one or more fibrates, one or more glycerolipids, and one or more digestion enhancers. The disclosed glycerolipids comprise one or more hard fats and one or more liquid fats. The disclosed digestion enhancers comprise one or more bile acids, one or more phospholipids, one or more free C14-24 fatty acids, one or more free C14-24 fatty acid surfactants, or any combination thereof. The present specification also discloses methods and procedures to formulate the disclosed one or more fibrates into the disclosed pharmaceutical compositions. The present specification further discloses methods and uses of the disclosed pharmaceutical compositions in the treatment of an inflammation and/or neuroinflammation.
La présente invention divulgue une composition pharmaceutique comprenant un ou plusieurs fibrates, un ou plusieurs glycérolipides et un ou plusieurs activateurs de digestion. Les glycérolipides divulgués comprennent une ou plusieurs graisses solides et une ou plusieurs graisses liquides. Les amplificateurs de digestion divulgués comprennent un ou plusieurs acides biliaires, un ou plusieurs phospholipides, un ou plusieurs acides gras libres en C14-24, un ou plusieurs tensioactifs d'acides gras libres en C14-24 ou une combinaison quelconque associée. La présente invention divulgue également des méthodes et des procédures destinées à formuler lesdits un ou plusieurs fibrates divulgués dans les compositions pharmaceutiques divulguées. La présente invention divulgue en outre des méthodes et des utilisations des compositions pharmaceutiques divulguées dans le traitement d'une inflammation et/ou d'une neuro-inflammation. |
| Author | GOODING, Daniel BREW, John BANNISTER, Robin M |
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| RelatedCompanies | TRX BIOSCIENCES LIMITED |
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| Snippet | The present specification discloses pharmaceutical composition disclosed herein comprises one or more fibrates, one or more glycerolipids, and one or more... |
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| Title | COMPOSITIONS HAVING IMPROVED BIOAVAILABILITY OF THERAPEUTICS AND USES THEREOF |
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