CORONAVIRUS IMMUNOGEN COMPOSITIONS AND THEIR USES

The disclosure provides compositions and methods comprising circular polyribonucleotides comprising a sequence encoding a coronavirus immunogen, and compositions and methods comprising linear polyribonucleotides comprising a sequence encoding one or more coronavirus immunogens. Compositions and meth...

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Main Authors SIGOVA, Alla Alexeevna, MELFI, Michael Donato, NELSON, Jennifer A, KAHVEJIAN, Avak, DE BOER, Alexandra Sophie, ECHELARD, Yann Paul Guy Régis, LEE, Soohyun, MOSAHEB, Mohammad Mubeen
Format Patent
LanguageEnglish
French
Published 01.06.2023
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Abstract The disclosure provides compositions and methods comprising circular polyribonucleotides comprising a sequence encoding a coronavirus immunogen, and compositions and methods comprising linear polyribonucleotides comprising a sequence encoding one or more coronavirus immunogens. Compositions and methods are provided that are related to generating polyclonal antibodies, for example, using the disclosed circular polyribonucleotides or the disclosed linear polyribonucleotides. L'invention concerne des compositions et des procédés comprenant des polyribonucléotides circulaires comportant une séquence codant pour un immunogène de coronavirus, et des compositions et des procédés comprenant des polyribonucléotides linéaires comportant une séquence codant pour un ou plusieurs immunogènes de coronavirus. L'invention concerne également des compositions et des procédés qui sont associés à la génération d'anticorps polyclonaux, par exemple, à l'aide des polyribonucléotides circulaires décrits ou des polyribonucléotides linéaires décrits.
AbstractList The disclosure provides compositions and methods comprising circular polyribonucleotides comprising a sequence encoding a coronavirus immunogen, and compositions and methods comprising linear polyribonucleotides comprising a sequence encoding one or more coronavirus immunogens. Compositions and methods are provided that are related to generating polyclonal antibodies, for example, using the disclosed circular polyribonucleotides or the disclosed linear polyribonucleotides. L'invention concerne des compositions et des procédés comprenant des polyribonucléotides circulaires comportant une séquence codant pour un immunogène de coronavirus, et des compositions et des procédés comprenant des polyribonucléotides linéaires comportant une séquence codant pour un ou plusieurs immunogènes de coronavirus. L'invention concerne également des compositions et des procédés qui sont associés à la génération d'anticorps polyclonaux, par exemple, à l'aide des polyribonucléotides circulaires décrits ou des polyribonucléotides linéaires décrits.
Author SIGOVA, Alla Alexeevna
DE BOER, Alexandra Sophie
MELFI, Michael Donato
MOSAHEB, Mohammad Mubeen
NELSON, Jennifer A
KAHVEJIAN, Avak
LEE, Soohyun
ECHELARD, Yann Paul Guy Régis
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– fullname: ECHELARD, Yann Paul Guy Régis
– fullname: LEE, Soohyun
– fullname: MOSAHEB, Mohammad Mubeen
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DocumentTitleAlternate COMPOSITIONS IMMUNOGÈNES DE CORONAVIRUS ET LEURS UTILISATIONS
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RelatedCompanies FLAGSHIP PIONEERING INNOVATION VI, LLC
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Snippet The disclosure provides compositions and methods comprising circular polyribonucleotides comprising a sequence encoding a coronavirus immunogen, and...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title CORONAVIRUS IMMUNOGEN COMPOSITIONS AND THEIR USES
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