A GENOTYPIC ASSAY TO SUBSPECIATE MYCOBACTERIUM ABSCESSUS COMPLEX STRAINS AND DETERMINE MACROLIDE RESISTANCE

• Main Authors: KREISWIRTH, Barry, MARRAS, Salvatore, CHEN, Liang
• Format: Patent
• Language: English; French
• Published: 10.11.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

A robust and rapid detection assay for the subspeciation of Mycobacterium abscessus is provided. The assay allows for three subspecies of M. abscessus to be detected, namely, M. abscessus subsp. abscessus, M. abscessus subsp. massiliense, and M. abscessus subsp. bolletii. Molecular beacon probes and...