FGFR3 INHIBITOR COMPOUNDS
The present invention provides compounds of the formula:, for use in the treatment of systemic sclerosis, fibrosis (e.g. pulmonary fibrosis), achondroplasia, thanatophoric dysplasia (e.g. type I), severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN), muenke syndrome or ca...
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| Main Authors | , , , , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
09.09.2022
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention provides compounds of the formula:, for use in the treatment of systemic sclerosis, fibrosis (e.g. pulmonary fibrosis), achondroplasia, thanatophoric dysplasia (e.g. type I), severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN), muenke syndrome or cancer.
La présente invention concerne des composés de formule : destinés à être utilisés dans le traitement de la sclérodermie généralisée, de la fibrose (par exemple, la fibrose pulmonaire), l'achondroplasie, la dysplasie thanatophore (par exemple, de type I), l'achondroplasie sévère avec un retard de développement et une acanthosis nigricans (SADDAN), le syndrome de Muenke ou le cancer. |
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| AbstractList | The present invention provides compounds of the formula:, for use in the treatment of systemic sclerosis, fibrosis (e.g. pulmonary fibrosis), achondroplasia, thanatophoric dysplasia (e.g. type I), severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN), muenke syndrome or cancer.
La présente invention concerne des composés de formule : destinés à être utilisés dans le traitement de la sclérodermie généralisée, de la fibrose (par exemple, la fibrose pulmonaire), l'achondroplasie, la dysplasie thanatophore (par exemple, de type I), l'achondroplasie sévère avec un retard de développement et une acanthosis nigricans (SADDAN), le syndrome de Muenke ou le cancer. |
| Author | METCALF, Andrew Terrance DILGER, Andrew Karl WALLS, Shane Michael URKALAN, Kaveri Balan KERCHER, Timothy Scott HAZLITT, Robert Alan BUME, Desta Doro CONDROSKI, Kevin Ronald ABRAHAM, Adedoyin David |
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| DocumentTitleAlternate | COMPOSÉS INHIBITEURS DE FGFR3 |
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| Notes | Application Number: WO2022US18644 |
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| Snippet | The present invention provides compounds of the formula:, for use in the treatment of systemic sclerosis, fibrosis (e.g. pulmonary fibrosis), achondroplasia,... |
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| SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | FGFR3 INHIBITOR COMPOUNDS |
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