MODULATING BHLHE40 IN THE DIFFERENTIATION OF TYPE 1 REGULATORY T CELLS AND CONTROLLING T CELL EXHAUSTION

Methods and cell compositions are provided in which expression of BHLHE40is modulated to direct T cell phenotype and function. L'invention concerne des procédés et des compositions cellulaires dans lesquels l'expression de BHLHE40 est modulée pour orienter le phénotype et la fonction des l...

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Bibliographic Details
Main Authors RONCAROLO, Maria Grazia, FREEBORN, Robert, UYEDA, Molly Kathryn Javier
Format Patent
LanguageEnglish
French
Published 19.05.2022
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Methods and cell compositions are provided in which expression of BHLHE40is modulated to direct T cell phenotype and function. L'invention concerne des procédés et des compositions cellulaires dans lesquels l'expression de BHLHE40 est modulée pour orienter le phénotype et la fonction des lymphocytes T.
Bibliography:Application Number: WO2021US59137