IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATED CAPSULAR SACCHARIDE ANTIGENS AND USES THEREOF

The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions and uses thereof. Immunogenic compositions of the present invention will typically comprise at le...

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Main Authors LOTVIN, Jason Arnold, DUTTA, Kaushik, SACKETT, Kelly Jeffrey, BROWN, Paul Wayne
Format Patent
LanguageEnglish
French
Published 19.05.2022
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Abstract The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumococcal infections using said novel immunogenic compositions. La présente invention concerne de nouvelles compositions immunogènes comprenant des antigènes (glycoconjugués) saccharidiques capsulaires de Streptococcus pneumoniae conjugués, des kits comprenant lesdites compositions immunogènes et leurs utilisations. Les compositions immunogènes de la présente invention comprennent généralement au moins un glycoconjugué d'un sérotype de S. pneumoniae que l'on ne trouve pas dans PREVNAR®, SYNFLORIX® et/ou PREVNAR 13®. L'invention concerne également la vaccination de sujets humains, en particulier des nourrissons et des personnes âgées, contre des infections pneumococciques à l'aide desdites nouvelles compositions immunogènes.
AbstractList The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumococcal infections using said novel immunogenic compositions. La présente invention concerne de nouvelles compositions immunogènes comprenant des antigènes (glycoconjugués) saccharidiques capsulaires de Streptococcus pneumoniae conjugués, des kits comprenant lesdites compositions immunogènes et leurs utilisations. Les compositions immunogènes de la présente invention comprennent généralement au moins un glycoconjugué d'un sérotype de S. pneumoniae que l'on ne trouve pas dans PREVNAR®, SYNFLORIX® et/ou PREVNAR 13®. L'invention concerne également la vaccination de sujets humains, en particulier des nourrissons et des personnes âgées, contre des infections pneumococciques à l'aide desdites nouvelles compositions immunogènes.
Author SACKETT, Kelly Jeffrey
LOTVIN, Jason Arnold
BROWN, Paul Wayne
DUTTA, Kaushik
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DocumentTitleAlternate COMPOSITIONS IMMUNOGÈNES COMPRENANT DES ANTIGÈNES SACCHARIDIQUES CAPSULAIRES CONJUGUÉS ET LEURS UTILISATIONS
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Snippet The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates),...
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SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATED CAPSULAR SACCHARIDE ANTIGENS AND USES THEREOF
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