NEW FYN AND VEGFR2 KINASE INHIBITORS

The invention relates to a N-phenylcarbamoyl compound of Formula (I) or a pharmaceutically acceptable salt thereof for use in the inhibition of at least one of tyrosine kinase selected from Fyn and VEGFR2 in the treatment of diseases and disorders involved with one or both kinases. L'invention...

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Main Authors BOVINO, Clara, MAGARACI, Filippo, ROVATI, Lucio Claudio, COLACE, Fabrizio, MANDELLI, Stefano, MENNUNI, Laura, ARTUSI, Roberto, BUZZI, Benedetta, CASELLI, Gianfranco
Format Patent
LanguageEnglish
French
Published 14.07.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to a N-phenylcarbamoyl compound of Formula (I) or a pharmaceutically acceptable salt thereof for use in the inhibition of at least one of tyrosine kinase selected from Fyn and VEGFR2 in the treatment of diseases and disorders involved with one or both kinases. L'invention concerne un composé N-phénylcarbamoyle de formule (I) ou un sel pharmaceutiquement acceptable de celui-ci, destiné à être utilisé dans l'inhibition d'au moins l'une des tyrosine kinases choisies parmi Fyn et VEGFR2 dans le traitement de maladies et de troubles dans lesquels l'une ou les deux kinases sont impliquées.
Bibliography:Application Number: WO2020EP84847