SOLID FORMS OF FILGOTINIB MALEATE AND PROCESSES THEREOF

• Main Authors: NEKKANTI, Satish Chowdary, THIRUNAHARI, Satyanarayana, MUDAPAKA, Vamsi Krishna
• Format: Patent
• Language: English; French
• Published: 11.03.2021
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Aspects of the present application relate to solid forms of Filgotinib maleate and pharmaceutical compositions thereof. Specific aspects of the present application relate to crystalline forms FM1, FM2 and FM3 of Filgotinib maleate characterized by X-ray diffraction patterns. Further aspect of the present application related to processes for the preparation of said crystalline forms of Filgotinib maleate. Des aspects de la présente invention concernent des formes solides de maléate de filgotinib et des compositions pharmaceutiques associées. Des aspects spécifiques de la présente invention concernent des formes cristallines FM1, FM2 et FM3 de maléate de filgotinib caractérisées par des motifs de diffraction des rayons X. Un autre aspect de la présente invention concerne des procédés de préparation desdites formes cristallines de maléate de filgotinib.