COMPOUNDS, COMPOSITIONS, AND METHODS OF USE
Described herein are compounds that act as CYP46A1 inhibitors, compositions comprising these compounds, and methods of their use into treating neurodegenerative diseases and the like, or a pharmaceutically active salt thereof. The present invention relates to compounds represented by the formula whe...
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| Main Authors | , , |
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| Format | Patent |
| Language | English French |
| Published |
03.12.2020
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Described herein are compounds that act as CYP46A1 inhibitors, compositions comprising these compounds, and methods of their use into treating neurodegenerative diseases and the like, or a pharmaceutically active salt thereof. The present invention relates to compounds represented by the formula wherein each symbol is as defined in the specification, or a pharmaceutically active salt thereof.
L'invention concerne des composés qui agissent en tant qu'inhibiteurs de CYP46A1, des compositions comprenant ces composés et des procédés d'utilisation de ceux-ci dans le traitement de maladies neurodégénératives et analogues, ou un sel pharmaceutiquement actif de ceux-ci. La présente invention concerne des composés représentés par la formule, dans laquelle chaque symbole est tel que défini dans la description, ou un sel pharmaceutiquement actif de ceux-ci. |
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| AbstractList | Described herein are compounds that act as CYP46A1 inhibitors, compositions comprising these compounds, and methods of their use into treating neurodegenerative diseases and the like, or a pharmaceutically active salt thereof. The present invention relates to compounds represented by the formula wherein each symbol is as defined in the specification, or a pharmaceutically active salt thereof.
L'invention concerne des composés qui agissent en tant qu'inhibiteurs de CYP46A1, des compositions comprenant ces composés et des procédés d'utilisation de ceux-ci dans le traitement de maladies neurodégénératives et analogues, ou un sel pharmaceutiquement actif de ceux-ci. La présente invention concerne des composés représentés par la formule, dans laquelle chaque symbole est tel que défini dans la description, ou un sel pharmaceutiquement actif de ceux-ci. |
| Author | LA, Daniel MISCHKE, Steven HOPPER, Allen |
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| RelatedCompanies | SAGE THERAPEUTICS, INC |
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| Snippet | Described herein are compounds that act as CYP46A1 inhibitors, compositions comprising these compounds, and methods of their use into treating... |
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| SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE |
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