COMPOUNDS, COMPOSITIONS, AND METHODS OF USE

Described herein are compounds that act as CYP46A1 inhibitors, compositions comprising these compounds, and methods of their use into treating neurodegenerative diseases and the like, or a pharmaceutically active salt thereof. The present invention relates to compounds represented by the formula whe...

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Bibliographic Details
Main Authors HOPPER, Allen, MISCHKE, Steven, LA, Daniel
Format Patent
LanguageEnglish
French
Published 03.12.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Described herein are compounds that act as CYP46A1 inhibitors, compositions comprising these compounds, and methods of their use into treating neurodegenerative diseases and the like, or a pharmaceutically active salt thereof. The present invention relates to compounds represented by the formula wherein each symbol is as defined in the specification, or a pharmaceutically active salt thereof. L'invention concerne des composés qui agissent en tant qu'inhibiteurs de CYP46A1, des compositions comprenant ces composés et des procédés d'utilisation de ceux-ci dans le traitement de maladies neurodégénératives et analogues, ou un sel pharmaceutiquement actif de ceux-ci. La présente invention concerne des composés représentés par la formule, dans laquelle chaque symbole est tel que défini dans la description, ou un sel pharmaceutiquement actif de ceux-ci.
Bibliography:Application Number: WO2020US34434