EXPRESSION VECTORS FOR EUKARYOTIC EXPRESSION SYSTEMS

The invention provides expression vectors for expressing multi-chain recombinant proteins (e.g., biologics) in mammalian cells. Also provided are host cells comprising the expression vectors, methods of producing the multi-chain recombinant proteins, and methods of propagating the expression vectors...

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Main Authors GUPTA, Balrina, DU, Zhimei, HUHN, Steven
Format Patent
LanguageEnglish
French
Published 25.06.2020
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Abstract The invention provides expression vectors for expressing multi-chain recombinant proteins (e.g., biologics) in mammalian cells. Also provided are host cells comprising the expression vectors, methods of producing the multi-chain recombinant proteins, and methods of propagating the expression vectors. L'invention concerne des vecteurs d'expression pour exprimer des protéines recombinées à chaînes multiples (par exemple des produits biologiques) dans des cellules de mammifère. L'invention concerne également des cellules hôtes comprenant les vecteurs d'expression, des procédés de production des protéines recombinées à chaînes multiples et des procédés de propagation des vecteurs d'expression.
AbstractList The invention provides expression vectors for expressing multi-chain recombinant proteins (e.g., biologics) in mammalian cells. Also provided are host cells comprising the expression vectors, methods of producing the multi-chain recombinant proteins, and methods of propagating the expression vectors. L'invention concerne des vecteurs d'expression pour exprimer des protéines recombinées à chaînes multiples (par exemple des produits biologiques) dans des cellules de mammifère. L'invention concerne également des cellules hôtes comprenant les vecteurs d'expression, des procédés de production des protéines recombinées à chaînes multiples et des procédés de propagation des vecteurs d'expression.
Author HUHN, Steven
GUPTA, Balrina
DU, Zhimei
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DocumentTitleAlternate VECTEURS D'EXPRESSION POUR SYSTÈMES D'EXPRESSION EUCARYOTES
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MERCK SHARP & DOHME CORP
GUPTA, Balrina
DU, Zhimei
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Snippet The invention provides expression vectors for expressing multi-chain recombinant proteins (e.g., biologics) in mammalian cells. Also provided are host cells...
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SubjectTerms BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Title EXPRESSION VECTORS FOR EUKARYOTIC EXPRESSION SYSTEMS
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