BENZIMIDAZOLONE DERIVATIVES, AND ANALOGUES THEREOF, AS IL-17 MODULATORS

A series of substituted benzimidazol-2-one derivatives, and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders. Une série de dérivés de benzimidaz...

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Main Authors SELBY, Matthew Duncan, LECOMTE, Fabien Claude
Format Patent
LanguageEnglish
French
Published 18.06.2020
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Abstract A series of substituted benzimidazol-2-one derivatives, and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders. Une série de dérivés de benzimidazole-2-one substitués, et des analogues de ceux-ci, sont de puissants modulateurs de l'activité de l'IL-17 humaine, et sont par conséquent utiles dans le traitement et/ou la prévention de diverses maladies humaines, y compris des troubles inflammatoires et auto-immuns.
AbstractList A series of substituted benzimidazol-2-one derivatives, and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders. Une série de dérivés de benzimidazole-2-one substitués, et des analogues de ceux-ci, sont de puissants modulateurs de l'activité de l'IL-17 humaine, et sont par conséquent utiles dans le traitement et/ou la prévention de diverses maladies humaines, y compris des troubles inflammatoires et auto-immuns.
Author LECOMTE, Fabien Claude
SELBY, Matthew Duncan
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DocumentTitleAlternate DÉRIVÉS DE BENZIMIDAZOLONE, ET ANALOGUES DE CEUX-CI, EN TANT QUE MODULATEURS D'IL-17
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Snippet A series of substituted benzimidazol-2-one derivatives, and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title BENZIMIDAZOLONE DERIVATIVES, AND ANALOGUES THEREOF, AS IL-17 MODULATORS
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