TEVERELIX-TFA COMPOSITION

The present invention relates to a teverelix-TFA composition having a molar ratio of teverelix to trifluoroacetate composition of at least 1:2.2. Such a molar ratio will prevent undesirable gel-formation and provide a homogenous suspension, whereby a unique bioavailablity of teverelix is obtained. L...

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Bibliographic Details
Main Authors POLAND, Guy, BOUTIGNON, François
Format Patent
LanguageEnglish
French
Published 09.01.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a teverelix-TFA composition having a molar ratio of teverelix to trifluoroacetate composition of at least 1:2.2. Such a molar ratio will prevent undesirable gel-formation and provide a homogenous suspension, whereby a unique bioavailablity of teverelix is obtained. La présente invention concerne une composition de tévérélix-TFA présentant un rapport molaire entre le tévérélix et le trifluoroacétate d'au moins 1:2,2. Un tel rapport molaire empêchera la formation de gel indésirable et fournira une suspension homogène, ce qui permettra d'obtenir une biodisponibilité unique du tévérélix.
Bibliography:Application Number: WO2019EP67728