COMPOUNDS FOR MODULATING DDAH AND ADMA LEVELS, AS WELL AS METHODS OF USING THEREOF TO TREAT DISEASE

Disclosed are compounds that can modulate DDAH and the amount of asymmetric dimethylarginine (ADMA) in a subject. Also provided are pharmaceutical compositions comprising these compounds, as well as methods of using these compositions to treat and/or prevent diseases associated with elevated or low...

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Bibliographic Details
Main Authors FOWLER, Kerry W, SINGH, Jaipal
Format Patent
LanguageEnglish
French
Published 07.11.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Disclosed are compounds that can modulate DDAH and the amount of asymmetric dimethylarginine (ADMA) in a subject. Also provided are pharmaceutical compositions comprising these compounds, as well as methods of using these compositions to treat and/or prevent diseases associated with elevated or low levels of DDAH and ADMA. L'invention concerne des composés qui peuvent moduler la DDAH et la quantité de diméthylarginine asymétrique (ADMA) chez un sujet. L'invention concerne également des compositions pharmaceutiques comprenant ces composés, ainsi que des méthodes d'utilisation de ces compositions pour traiter et/ou prévenir des maladies associées à des taux élevés ou faibles de DDAH et d'ADMA.
Bibliography:Application Number: WO2019US30020