COMPOSITIONS AND METHODS TO TREAT CANCER

• Main Authors: DEWECK, Antoine, BILLY, Eric, HOFMANN, Francesco, MAVRAKIS, Konstantinos John, GOLJI, Javad, KAUFFMANN, Audrey, MCDONALD III, Earl Robert, STEGMEIER, Frank Peter, HOFFMAN, Gregory, SCHMELZLE, Tobias, SCHLABACH JR., Michael Ray, SELLERS, William
• Format: Patent
• Language: English; French
• Published: 21.03.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

The disclosure provides novel personalized therapies, kits, transmittable forms of information and methods for use in treating patients having cancer, wherein the cancer is amenable to therapeutic treatment with an inhibitor, e.g., an inhibitor of any of the targets disclosed herein. Kits, methods of screening for candidate inhibitors, and associated methods of treatment are also provided. L'invention concerne de nouvelles thérapies personnalisées, des trousses, des formes transmissibles d'informations et des procédés destinés à être utilisés dans le traitement de patients atteints d'un cancer, le cancer pouvant faire l'objet d'un traitement thérapeutique avec un inhibiteur, par exemple un inhibiteur de l'une quelconque des cibles décrites ici. L'invention concerne également des trousses, des procédés de criblage d'inhibiteurs candidats et des procédés associés de traitement.