SELECTIVE PULLDOWN OF CHROMATIN FRAGMENTS

The present invention provides methods for the selective isolation of target nucleoprotein fragments under native conditions through the combined use of single strand invasion and LNA-comprising specific probes. The method is considered to be especially useful for the isolation of target nucleoprote...

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Bibliographic Details
Main Authors VAN NOORT, John, HERMANS, Nicolaas
Format Patent
LanguageEnglish
French
Published 09.11.2017
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:The present invention provides methods for the selective isolation of target nucleoprotein fragments under native conditions through the combined use of single strand invasion and LNA-comprising specific probes. The method is considered to be especially useful for the isolation of target nucleoprotein fragments for single molecule force analysis. La présente invention concerne des procédés d'isolement sélectif de fragments cibles de nucléoprotéines dans des conditions natives par l'utilisation combinée de l'invasion de brins uniques et de sondes spécifiques à LNA. Le procédé est considéré comme étant particulièrement utile pour l'isolement de fragments cibles de nucléoprotéines pour l'analyse de force de molécules uniques.
Bibliography:Application Number: WO2017EP60533