CD38 INHIBITORS AND METHODS OF TREATMENT

Compounds of Formula (I) and methods of treating diseases of metabolism by modulating cellular NAD+ levels through the inhibition of the CD38 enzyme, are disclosed. Formula (I). L'invention concerne des composés de formule I et des méthodes de traitement de maladies du métabolisme, par modulati...

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Main Authors HAFFNER, CURT, BECHERER, J. DAVID, CADILLA, RODOLFO, DEATON, DAVID NORMAN, SCHULTE, CHRISTIE, HENKE, BRAD RICHARD, PREUGSCHAT, FRANK
Format Patent
LanguageEnglish
French
Published 09.06.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Compounds of Formula (I) and methods of treating diseases of metabolism by modulating cellular NAD+ levels through the inhibition of the CD38 enzyme, are disclosed. Formula (I). L'invention concerne des composés de formule I et des méthodes de traitement de maladies du métabolisme, par modulation des niveaux de NAD+ cellulaire par inhibition de l'enzyme CD38. Formule I
Bibliography:Application Number: WO2015IB58965