BIOMARKER FOR PREDICTING SENSITIVITY TO PROTEIN KINASE INHIBITOR AND USE THEREOF

• Main Authors: HA, SEUNG HEE, LEE, JAE LYUN, PARK, SEONG JOON, KIM, TAE WON, JUNG, SEANG HWAN, LEE, HA REUM, CHOI, EUN KYUNG, SHIN, JAE SIK, KIM, BONG CHOEL, KIM, SEUNG MI, MOON, JAI HEE, JUNG, SOO A, HONG, YONG SANG, KIM, KYU PYO, JIN, DONG HOON, LEE, DAE HEE, KIM, JEONG EUN, HONG, SEUNG WOO, CHOI, EUN KYOUNG, JUNG, HA NA, LEE, JUNG SHIN
• Format: Patent
• Language: English; French; Korean
• Published: 10.03.2016
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to a biomarker for predicting sensitivity to a protein kinase inhibitor and a use thereof, and provides a marker for predicting sensitivity to a protein kinase inhibitor, a composition, a kit, and a prediction method. According to the present invention, an effect of predicting sensitivity to a protein kinase inhibitor is excellent, and thus the present invention can be useful for cancer treatment. La présente invention concerne un biomarqueur pour prédire la sensibilité à un inhibiteur de protéine kinase et une utilisation de celui-ci, et concerne un marqueur pour prédire la sensibilité à un inhibiteur de protéine kinase, une composition, un kit, et un procédé de prédiction. Selon la présente invention, un effet de prédiction de la sensibilité à un inhibiteur de protéine kinase est excellent et, par conséquent, la présente invention peut être utile pour le traitement du cancer. 본 발명은 단백질 키나제 억제제에 대한 감수성 예측용 바이오 마커 및 이의 용도에 관한 것으로, 단백질 키나제 억제제에 대한 감수성 예측용 마커, 조성물, 키트 및 예측 방법을 제공한다. 본 발명에 따르면, 단백질 키나제 억제제에 대한 감수성 예측 효과가 우수하므로, 본 발명은 암 치료에 유용하게 이용될 수 있다.