COMPOSITIONS AND METHOD FOR TREATING THROMBOSIS

A peptide, derivative or peptidomimetic the blocks binding of GNA12 to αSNAP is provided as are methods of using the same to inhibit thrombin-induced von Willebrand Factor secretion and prevent or treat thrombosis. L'invention concerne un peptide, dérivé ou peptidomimétique bloquant la liaison...

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Main Authors MINSHALL, RICHARD, D, RUSU, LUIZA
Format Patent
LanguageEnglish
French
Published 11.12.2014
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Abstract A peptide, derivative or peptidomimetic the blocks binding of GNA12 to αSNAP is provided as are methods of using the same to inhibit thrombin-induced von Willebrand Factor secretion and prevent or treat thrombosis. L'invention concerne un peptide, dérivé ou peptidomimétique bloquant la liaison de GNA12 à la αSNAP, ainsi que des procédés d'utilisation de ceux-ci pour inhiber la sécrétion du facteur de von Willebrand (vWF) induite par la thrombine et pour prévenir ou traiter la thrombose.
AbstractList A peptide, derivative or peptidomimetic the blocks binding of GNA12 to αSNAP is provided as are methods of using the same to inhibit thrombin-induced von Willebrand Factor secretion and prevent or treat thrombosis. L'invention concerne un peptide, dérivé ou peptidomimétique bloquant la liaison de GNA12 à la αSNAP, ainsi que des procédés d'utilisation de ceux-ci pour inhiber la sécrétion du facteur de von Willebrand (vWF) induite par la thrombine et pour prévenir ou traiter la thrombose.
Author RUSU, LUIZA
MINSHALL, RICHARD, D
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DocumentTitleAlternate COMPOSITIONS ET MÉTHODE DE TRAITEMENT DE LA THROMBOSE
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Title COMPOSITIONS AND METHOD FOR TREATING THROMBOSIS
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