COMPOSITIONS AND METHOD FOR TREATING THROMBOSIS

A peptide, derivative or peptidomimetic the blocks binding of GNA12 to αSNAP is provided as are methods of using the same to inhibit thrombin-induced von Willebrand Factor secretion and prevent or treat thrombosis. L'invention concerne un peptide, dérivé ou peptidomimétique bloquant la liaison...

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Bibliographic Details
Main Authors MINSHALL, RICHARD, D, RUSU, LUIZA
Format Patent
LanguageEnglish
French
Published 11.12.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A peptide, derivative or peptidomimetic the blocks binding of GNA12 to αSNAP is provided as are methods of using the same to inhibit thrombin-induced von Willebrand Factor secretion and prevent or treat thrombosis. L'invention concerne un peptide, dérivé ou peptidomimétique bloquant la liaison de GNA12 à la αSNAP, ainsi que des procédés d'utilisation de ceux-ci pour inhiber la sécrétion du facteur de von Willebrand (vWF) induite par la thrombine et pour prévenir ou traiter la thrombose.
Bibliography:Application Number: WO2014US34621