HUMAN ANTI-TAU ANTIBODIES

Provided are novel human tau-specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for tau are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments,...

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Main Authors MONTRASIO, FABIO, WEINREB, PAUL, H, CHEN, FENG, GARBER, ELLEN, A, GRIMM, JAN
Format Patent
LanguageEnglish
French
Published 26.06.2014
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Provided are novel human tau-specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for tau are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for tau targeted immunotherapy and diagnosis, respectively. L'invention concerne de nouveaux anticorps humains spécifiques de tau ainsi que des fragments, dérivés et variants associés, ainsi que des procédés associés. L'invention concerne également des dosages, des kits et des supports solides associés aux anticorps spécifiques de tau. L'anticorps, la ou les chaînes d'immunoglobuline, ainsi que les fragments de liaison, dérivés et variants associés, peuvent être utilisés dans des compositions pharmaceutiques et de diagnostic pour l'immunothérapie et le diagnostic ciblés de tau, respectivement.
Bibliography:Application Number: WO2013US76952