METHOD FOR PRODUCING LEISHMANIA RECOMBINANT PROTEINS AND USE IN A DIAGNOSTIC KIT AND VACCINE AGAINST LEISHMANIASES

• Main Authors: BARTHOLOMEU, DANIELLA CASTANHEIRA, SILVA, ANA LUIZA TEIXEIRA, BUENO, LILIAN LACERDA, GOMES, MATHEUS DE SOUZA, FUJIWARA, RICARDO TOSHIO, SOUZA, DANIEL MENEZES
• Format: Patent
• Language: English; French; Portuguese
• Published: 19.06.2014
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to the use of recombinant HSP 83-1, MAPK and MAPK3 antigens, proteins present in protozoa of the Leishmania genus, for producing vaccines and a leishmaniasis diagnostic kits for humans and/or dogs. These antigens were selected by bioinformatics analysis involving immuno...