HUMAN MONOCLONAL ANTIBODIES AGAINST HUMAN CHEMOKINE RECEPTOR CCR6

Aspects of this invention include fully human antibodies or fragments thereof that bind specifically to human CCR6 receptor. Such antibodies or fragments thereof can be used to treat disorders involving over function of the CCR6 receptor, including cancers, inflammatory diseases and fibrotic disease...

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Main Authors KIM, ELDAR, IVANOVA, EKATERINA, OVCHINNIKOVA, ELENA, MIKHAYLOV, ROMAN, ABBASOVA, SVETLANA, ULITIN, ANDRE, VASILYEVA, VIKTORIIA
Format Patent
LanguageEnglish
French
Published 12.12.2013
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Aspects of this invention include fully human antibodies or fragments thereof that bind specifically to human CCR6 receptor. Such antibodies or fragments thereof can be used to treat disorders involving over function of the CCR6 receptor, including cancers, inflammatory diseases and fibrotic diseases. Other uses include detection of human CCR6 receptor in biological samples for diagnostic or evaluative purposes. Selon certains aspects, cette invention comprend des anticorps complètement humains, ou sur leurs fragments, qui se lient spécifiquement au récepteur CCR6 humain. De tels anticorps ou leurs fragments peuvent être utilisés pour traiter des troubles faisant intervenir un fonctionnement excédentaire du récepteur CCR6, comprenant des cancers, des maladies inflammatoires et des maladies fibreuses. L'invention concerne également d'autres utilisations comprenant la détection du récepteur CCR6 humain dans des échantillons biologiques à des fins de diagnostic ou d'évaluation.
Bibliography:Application Number: WO2013US31692