TETRAHYDROPYRAZOLOPYRIMIDINE COMPOUNDS

Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis Selon des modes de r...

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Main Authors SATOH, TAKASHI, CARLSON, ERIC, ISHIZAKA, SALLY, BOIVIN, ROCH, MACKEY, MATTHEW, HANSEN, HANS, SCHILLER, SHAWN, ENDO, ATSUSHI, HAWKINS, LYNN D, NARAYAN, SRIDHAR
Format Patent
LanguageEnglish
French
Published 05.12.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis Selon des modes de réalisation, l'invention concerne des composés tétrahydropyrazolopyrimidines qui agissent en tant qu'antagonistes ou en tant qu'inhibiteurs pour les récepteurs 7 et/ou 8 de type Toll, ainsi que leur utilisation dans des compositions pharmaceutiques efficaces pour le traitement du lupus érythémateux systémique (SLE) et de la néphrite lupique.
Bibliography:Application Number: WO2013US43679