GLUCAGON-LIKE PEPTIDE-2 COMPOSITIONS AND METHODS OF MAKING AND USING SAME

The present invention relates to compositions comprising GLP-2 protein or variants thereof linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in the trea...

Full description

Saved in:
Bibliographic Details
Main Authors SPINK, BENJAMIN, SCHELLENBERGER, VOLKER, SILVERMAN, JOSHUA, WANG, CHIA-WEI, STEMMER, WILLEM P, GEETHING, NATHAN
Format Patent
LanguageEnglish
French
Published 21.03.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to compositions comprising GLP-2 protein or variants thereof linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in the treatment of GLP-2-related conditions. La présente invention concerne des compositions comportant une protéine GLP-2 ou des variants de celle-ci liés à un polypeptide recombinant étendu (XTEN), des acides nucléiques isolés codant pour les compositions, et des vecteurs et des cellules hôtes contenant ceux-ci, ainsi que des procédés de fabrication et d'utilisation de telles compositions dans le traitement d'états associés à GLP-2.
Bibliography:Application Number: WO2012US54941