A SET OF MICRORNAS AS MARKERS AND TARGETS IN CANCER AND IMMUNE SYSTEM RELATED DISEASES, METHODS FOR THEIR APPLICATION AND A KIT

• Main Authors: KISAND, KAI, PIHLAP, MAIRE, RUNNEL, TOOMAS, TSEREL, LIINA, REBANE, ANA
• Format: Patent
• Language: English; French
• Published: 07.03.2013
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

The present invention involves detection of differential expression of specific microRNAs (miRNAs) in certain biological/pathological conditions, and functional applications of miR-511, miR-193b,miR-99b and other listed miRNAs as markers and targets in cancer and immune system related diseases. The microRNAs are used as an expression modulation targets for influencing proliferative properties of a cell and/or immune functions of an organism. Cette invention concerne la détection de l'expression différentielle de micro-ARN (miARN) spécifiques dans certaines conditions biologiques/ pathologiques, et les applications fonctionnelles du miR-511, miR-193b, miR-99b et autres miARN indiqués comme marqueurs et cibles dans le cancer et les maladies liées au système immunitaire. Les miARN sont utilisés comme cibles de modulation d'expression pour influencer les propriétés prolifératives d'une cellule et/ou les fonctions immunes d'un organisme.