ANTI-DIABETIC COMPOUNDS
The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diab...
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Main Authors | , , , , , , |
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Format | Patent |
Language | English French |
Published |
28.06.2012
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.
La présente invention concerne une molécule de FGF21 liée de façon covalente au site de combinaison d'un anticorps via un pont, ledit pont étant lié de façon covalente à la chaîne latérale d'un résidu de liaison au sein de FGF21. La présente invention concerne diverses utilisations des composés, y compris des méthodes de traitement prophylactique ou thérapeutique du diabète ou d'états pathologiques liés au diabète. |
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Bibliography: | Application Number: WO2011IB54874 |