PYRROLO- PYRAZINE DERIVATIVES USEFUL AS INHIBITORS OF ATR KINASE

• Main Authors: MACCORMICK, SOMHAIRLE, DURRANT, STEVEN, JOHN, FRAYSSE, DAMIEN, REAPER, PHILIP, MICHAEL, CHARRIER, JEAN-DAMIEN, PINDER, JOANNE, VIRANI, ANIZA, NIZARALI, KNEGTEL, RONALD, MARCELLUS ALPHONSUS
• Format: Patent
• Language: English; French
• Published: 29.12.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to pyrrolopyrazines compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the comp...