FORMULATION FOR ROOM TEMPERATURE STABILIZATION OF A LIVE ATTENUATED BACTERIAL VACCINE

This invention provides methods and compositions for stabilizing proteins and vaccines in dried formulations. In particular, a cavitation method and compositions of preparing a dried vaccine are provided that stabilize the viability of live bacteria and live virus vaccines at room temperature. Cette...

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Main Authors CHIUEH, GARY, SAXENA, ATUL, PHAM, BINH, OHTAKE, SATOSHI, LECHUGA-BALLESTEROS, DAVID, TRUONG-LE, VU, MARTIN, RUSSELL
Format Patent
LanguageEnglish
French
Published 29.11.2012
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This invention provides methods and compositions for stabilizing proteins and vaccines in dried formulations. In particular, a cavitation method and compositions of preparing a dried vaccine are provided that stabilize the viability of live bacteria and live virus vaccines at room temperature. Cette invention concerne des procédés et des compositions pour stabiliser des protéines et des vaccins dans des formulations séchées. En particulier, elle concerne un procédé de cavitation et des compositions pour préparer un vaccin séché, qui stabilisent la viabilité de vaccins à base de bactéries vivantes et de virus vivants à température ambiante.
Bibliography:Application Number: WO2010US48674