DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES

Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease. L'invention porte sur des dérivés d'un amide d'acide 6,7-dihydro-5...

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Main Authors LAWLOR, MICHAEL, DAVID, BRUNETTE, STEVEN, RICHARD, BARBOSA, ANTONIO, J.M, HORAN, JOSHUA, COURTNEY, KOWALSKI, JENNIFER, A, LEMIEUX, RENE, MARC, MCKIBBEN, BRYAN, MILLER, CRAIG, ANDREW
Format Patent
LanguageEnglish
French
Published 09.12.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease. L'invention porte sur des dérivés d'un amide d'acide 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylique qui présentent un bon effet inhibiteur sur l'interaction de CAM et de Leukointégrines et qui sont ainsi utiles dans le traitement d'une maladie inflammatoire.
Bibliography:Application Number: WO2010US36094