PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS

• Main Authors: MARSILJE III, THOMAS H, LEE, CHRISTIAN CHO-HUA, LU, WENSHUO, HE, XIAOHUI, YANG, KUNYONG, CHEN, BEI, JIANG, SONGCHUN
• Format: Patent
• Language: English; French
• Published: 01.04.2010
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The invention provides novel pyrimidine derivatives of formula I and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin- li...