MEDICAL DEVICES COMPRISING POLYMERIC DRUG DELIVERY SYSTEMS WITH DRUG SOLUBILITY GRADIENTS

• Main Authors: UDIPI, KISHORE, CHEN, MINGFEI, CHENG, PEIWEN
• Format: Patent
• Language: English; French
• Published: 12.11.2009
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP

Disclosed are drug delivery systems comprising drugs admixed with polymers having drug solubility gradients and methods of making the polymers. Also disclosed are medical devices having coatings thereon comprising the drug solubility gradient-containing polymers and at least one drug. La présente invention concerne des systèmes de délivrance de médicaments comprenant des médicaments mélangés à des polymères à gradients de solubilité de médicaments et des procédés pour fabriquer ces polymères. L'invention concerne également des dispositifs médicaux portant des revêtements comprenant des polymères contenant des gradients de solubilité de médicaments et au moins un médicament.