LYOPHILISED ANTIGEN COMPOSITION
The present invention provides lyophilised compositions comprising an antigen and a Toll- like receptor (TLR) 9 agonist. Such compositions may be reconstituted into immunogenic compositions for use in vaccination with a carrier selected from the group of particulate carriers consisting of liposomes,...
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| Main Author | |
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| Format | Patent |
| Language | English French |
| Published |
27.11.2008
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention provides lyophilised compositions comprising an antigen and a Toll- like receptor (TLR) 9 agonist. Such compositions may be reconstituted into immunogenic compositions for use in vaccination with a carrier selected from the group of particulate carriers consisting of liposomes, mineral salts, emulsions, polymers and ISCOMs. Methods of making immunogenic compositions from the lyophilised compositions of the invention and use of the same in immunisation are also herein provided.
La présente invention concerne des compositions lyophilisées renfermant un antigène et un agoniste d'un récepteur de type Toll (TLR) 9. De telles compositions peuvent être reconstituées en compositions immunogéniques en vue d'une utilisation dans une vaccination avec un support choisi dans le groupe des supports particulaires constitués de liposomes, sels minéraux, émulsions, polymères et ISCOM. L'invention concerne également des procédés de fabrication de compositions immunogéniques à partir des compositions lyophilisées de l'invention et l'utilisation de celles-ci dans une immunisation. |
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| AbstractList | The present invention provides lyophilised compositions comprising an antigen and a Toll- like receptor (TLR) 9 agonist. Such compositions may be reconstituted into immunogenic compositions for use in vaccination with a carrier selected from the group of particulate carriers consisting of liposomes, mineral salts, emulsions, polymers and ISCOMs. Methods of making immunogenic compositions from the lyophilised compositions of the invention and use of the same in immunisation are also herein provided.
La présente invention concerne des compositions lyophilisées renfermant un antigène et un agoniste d'un récepteur de type Toll (TLR) 9. De telles compositions peuvent être reconstituées en compositions immunogéniques en vue d'une utilisation dans une vaccination avec un support choisi dans le groupe des supports particulaires constitués de liposomes, sels minéraux, émulsions, polymères et ISCOM. L'invention concerne également des procédés de fabrication de compositions immunogéniques à partir des compositions lyophilisées de l'invention et l'utilisation de celles-ci dans une immunisation. |
| Author | LEMOINE, DOMINIQUE, INGRID |
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| DocumentTitleAlternate | COMPOSITION LYOPHILISÉE D'ANTIGÈNE |
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| Notes | Application Number: WO2008EP56305 |
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| RelatedCompanies | LEMOINE, DOMINIQUE, INGRID GLAXOSMITHKLINE BIOLOGICALS S.A |
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| Snippet | The present invention provides lyophilised compositions comprising an antigen and a Toll- like receptor (TLR) 9 agonist. Such compositions may be reconstituted... |
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| SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | LYOPHILISED ANTIGEN COMPOSITION |
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