NEW CONJUGATES FOR THERAPEUTIC PURPOSES AND/OR AS DIAGNOSIS AND/OR IMAGING AGENTS AND METHOD FOR PREPARING THE SAME
The invention relates to a method for preparing a conjugate of the general formula (I) or a derivative thereof, in which : P is a physiologically acceptable chemical or biological substrate selected from proteins, polysaccharides, liposome-type vectors or nano- and micro-particles or biocompatible p...
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Format | Patent |
Language | English French |
Published |
26.06.2008
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Abstract | The invention relates to a method for preparing a conjugate of the general formula (I) or a derivative thereof, in which : P is a physiologically acceptable chemical or biological substrate selected from proteins, polysaccharides, liposome-type vectors or nano- and micro-particles or biocompatible polymers; and Q is a physiologically acceptable chemical or biological entity different from P and of interest in the field of therapy, diagnosis and/or imaging and selected from targeting ligands, markers, marker-chelating agents and/or marker-chelating agents-marker pairs. The invention also relates to the use of such derivatives in the medical field and essentially for diagnosis and/or imaging purposes.
La présente invention concerne un procédé utile pour la préparation d'un conjugué de formule générale (I) ou l'un de ses dérivés: Formule (I) dans laquelle: -P représente un substrat, chimique ou biologique, physiologiquement acceptable choisi parmi les protéines, les polysaccharides, les vecteurs de type liposome, ou nano-et microparticules ou encore les polymères biocompatibles, et -Q représente une entité, chimique ou biologique, physiologiquement acceptable différente de P et d intérêt dans le domaine thérapeutique, du diagnostic et/ou de l'imagerie choisi parmi des ligands de ciblage, des marqueurs, des chélatants de marqueur(s) et/ou des couples de chélatant de marqueur(s) -marqueur, Elle vise en outre l'utilisation de tels dérivés dans le domaine médical et notamment à des fins de diagnostic et/ou d'imagerie. |
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AbstractList | The invention relates to a method for preparing a conjugate of the general formula (I) or a derivative thereof, in which : P is a physiologically acceptable chemical or biological substrate selected from proteins, polysaccharides, liposome-type vectors or nano- and micro-particles or biocompatible polymers; and Q is a physiologically acceptable chemical or biological entity different from P and of interest in the field of therapy, diagnosis and/or imaging and selected from targeting ligands, markers, marker-chelating agents and/or marker-chelating agents-marker pairs. The invention also relates to the use of such derivatives in the medical field and essentially for diagnosis and/or imaging purposes.
La présente invention concerne un procédé utile pour la préparation d'un conjugué de formule générale (I) ou l'un de ses dérivés: Formule (I) dans laquelle: -P représente un substrat, chimique ou biologique, physiologiquement acceptable choisi parmi les protéines, les polysaccharides, les vecteurs de type liposome, ou nano-et microparticules ou encore les polymères biocompatibles, et -Q représente une entité, chimique ou biologique, physiologiquement acceptable différente de P et d intérêt dans le domaine thérapeutique, du diagnostic et/ou de l'imagerie choisi parmi des ligands de ciblage, des marqueurs, des chélatants de marqueur(s) et/ou des couples de chélatant de marqueur(s) -marqueur, Elle vise en outre l'utilisation de tels dérivés dans le domaine médical et notamment à des fins de diagnostic et/ou d'imagerie. |
Author | BESSODES, MICHEL SCHERMAN, DANIEL CHAUMET-RIFFAUD, PHILIPPE |
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DocumentTitleAlternate | NOUVEAUX CONJUGUES, UTILISABLES A DES FINS THERAPEUTIQUES, ET/OU A TITRE D'AGENT DE DIAGNOSTIC ET/OU D'IMAGERIE ET LEUR PROCEDE DE PREPARATION |
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Notes | Application Number: WO2007FR52517 |
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RelatedCompanies | BESSODES, MICHEL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) SCHERMAN, DANIEL CHAUMET-RIFFAUD, PHILIPPE |
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Snippet | The invention relates to a method for preparing a conjugate of the general formula (I) or a derivative thereof, in which : P is a physiologically acceptable... |
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Title | NEW CONJUGATES FOR THERAPEUTIC PURPOSES AND/OR AS DIAGNOSIS AND/OR IMAGING AGENTS AND METHOD FOR PREPARING THE SAME |
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