QUINAZOLINE DERIVATIVES USED AS INHIBITORS OF ERBB TYROSINE KINASE

A quinazoline derivative of the Formula (I): wherein the substituents are as defined in the text for use in the production of an anti proliferative effect which effect is produced alone or in part by inhibiting erbB2 receptor tyrosine kinase in a warm blooded animal such as man. L'invention con...

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Bibliographic Details
Main Authors DUCRAY, RICHARD, BRADBURY, ROBERT, HUGH, BARLAAM, BERNARD, CHRISTOPHE
Format Patent
LanguageEnglish
French
Published 07.06.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A quinazoline derivative of the Formula (I): wherein the substituents are as defined in the text for use in the production of an anti proliferative effect which effect is produced alone or in part by inhibiting erbB2 receptor tyrosine kinase in a warm blooded animal such as man. L'invention concerne un dérivé de quinazoline de formule (I), dans laquelle les substituants sont tels que définis dans la description. Ce dérivé est destiné à produire un effet antiprolifératif, cet effet étant produit uniquement ou partiellement par inhibition des tyrosine kinases erbB2 associées au récepteur chez un animal à sang chaud, notamment un humain.
Bibliography:Application Number: WO2006GB04451